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Novartis’ Leqvio Shows Promise in Lowering Cholesterol

Novartis shares positive results from Phase III clinical trial evaluating twice-yearly Leqvio.

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By: Charlie Sternberg

Associate Editor

Novartis’ investigational drug, Leqvio (inclisiran), has demonstrated positive results in a Phase III clinical trial. The drug, which is administered twice yearly, significantly lowered low-density lipoprotein cholesterol (LDL-C) levels in patients at low or moderate risk of atherosclerotic cardiovascular disease (ASCVD).   The V-MONO study, which evaluated Leqvio as a monotherapy, compared its efficacy to both placebo and ezetimibe, a commonly used cholesterol-lowering medication. Patients en...

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